FOXO3 Inhibits Human Gastric Adenocarcinoma (AGS) Cell Growth by Promoting Autophagy in an Acidic Microenvironment
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چکیده
منابع مشابه
Nanoliposomal formulation of Ecballium elaterium Extract: Cytotoxic Evaluation against Human Gastric Adenocarcinoma (AGS) Cell Line
Objective(s): The aim of this study was to determine cytotoxic effect of nanoliposomal form of lyophilized aqueous extract of Ecballium elaterium fruit on gastric cell line (AGS) using cell viability tests. Methods: An aqueous extract of the fruits of Ecballium elaterium was prepared. Nanoliposomal form was also prepared by thin-film hydration...
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Objective(s): Gastric cancer is the third leading cause of cancer-related death worldwide. The overall survival rate of patients is poor because gastric cancers are usually diagnosed at the late stages. Therefore, further research is needed and appropriate research tools are required to develop novel therapeutic approaches.Materials and Methods: Eight female athymic nude mice with a C57BL/6 bac...
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BACKGROUND Gastric carcinoma is the second leading cause of cancer death. microRNAs play vital roles in regulating expression of related oncogenes. microRNA-25 (miR-25) has been found to be up-regulated in gastric carcinoma. However, its roles in affecting cell apoptosis of gastric carcinoma and the related mechanism remain elusive. This study aimed to uncover the influences of miR-25 on gastri...
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Background: Calprotectin is cytotoxic agent that its anti-tumor effects are governed through suppression of topoisomerase II a key enzyme in apoptosis. In previous studies, cytotoxicity and apoptotic effects of calprotectin are shown on different cancer cell lines, but not human gastric cancer cell lines. In the present study, cytotoxicity and apoptotic effects of calprotectin on human gastric ...
متن کاملnanoliposomal formulation of ecballium elaterium extract: cytotoxic evaluation against human gastric adenocarcinoma (ags) cell line
objective(s): the aim of this study was to determine cytotoxic effect of nanoliposomal form of lyophilized aqueous extract of ecballium elaterium fruit on gastric cell line (ags) using cell viability tests. methods: an aqueous extract of the fruits of ecballium elaterium was prepared. nanoliposomal form was also prepared by thin-film hydration method and stability size was determined by sem. th...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2018
ISSN: 1015-8987,1421-9778
DOI: 10.1159/000492884